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Thus, we suggest that the use of clarithromycin in copd exacerbations may either treat the infection or help control the inflammation. In vitro activity of clarithromycin, cefprozol, and other common oral antimicrobial agents against gram-positive and gram-negative pathogens. In most cases, it is considered bioequivalent to the brand name counterpart with respect to pharmacokinetic and pharmacodynamic properties. Therefore, antimicrobial therapy was changed to clarithromycjn (500 mg twice daily) for 6 months.
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